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From251US$ /night
Check-in
11Jan2026Select date
Check-out
12Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

167 West Main Street, Lexington, Kentucky, United States, 40507
-
Steps from the Lexington Convention Center
Great
8.2
8.7
/10
4.5
4.2
/5

Museum

21c Museum Hotel Lexington offers over 7,000 square feet of exhibition space showcasing solo and group exhibitions that reflect contemporary culture. Guests will find specially commissioned, site-specific works from various artists both inside and outside the hotel, including the illuminating Spectralline by SOFTlab. The museum's galleries rotate exhibitions regularly, encouraging repeat visits to discover new artworks.

Dining

Lockbox serves locally sourced dishes that highlight the culinary heritage of Kentucky, offering a unique dining experience. Guests enjoy daily breakfast credits along with a selection of cocktails and locally brewed beers. The hotel's food service includes options for private dining accessible through the restored bank safe, creating a distinct atmosphere.

Rooms

The hotel offers various room types including the Deluxe King featuring spacious designs and large historic windows. The Nightwatch room provides an immersive art environment while each room includes original artwork and Malin + Goetz bath amenities. Guests can choose from suites like the Skylight Suite, which includes a unique skylight and separate living space.

Location

21c Museum Hotel Lexington occupies the historic Fayette National Bank Building in downtown Lexington, providing convenient access to the city's cultural attractions. Guests can explore local breweries, the Kentucky Horse Park, and various galleries situated within a short distance. The hotel's position allows for easy discovery of Lexington's charms while being a central hub for local activities.

Events

With venues capable of hosting events for up to 250 guests, 21c offers beautiful light-filled spaces replete with contemporary art suitable for weddings and corporate meetings. Facilities include a large main gallery and five private galleries equipped with state-of-the-art audio-visual technology. Additionally, the hotel provides unique options such as bourbon tastings and art-filled scavenger hunts, enhancing the event experience.

Highlights

Dining: Lockbox serves locally sourced dishes

Rooms: Nightwatch offers an immersive experience

Events: Large main gallery accommodates up to 250 guests

Museum: More than 7,000 square feet of exhibition space

Location: Historic Fayette National Bank Building

Must-do experiences

  • Stroll through the Lexington Farmers Market on Saturdays for fresh local fare.
  • Indulge in a Hot Brown at the famous Lexington Diner for a true local dish.
  • Visit the Mary Todd Lincoln House to discover unique Kentucky history.
  • Explore the urban art at the 21C Museum Hotel that blends art and community.
  • Relax in the scenic parks of the Legacy Trail during a leisurely bike ride.
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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
City Queen Room
2 persons
22 m² 
1 King-size bed
Shower
Coffee machine
Deluxe Queen Room
2 persons
33 m² 
2 King Size Beds
Shower
Coffee machine
Deluxe King Room
2 persons
31 m² 
1 King-size bed
Shower
Coffee machine
Corner King Room
2 persons
40 m² 
1 King-size bed
Shower
Coffee machine
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Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Free Wi-Fi in public areas
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Yoga class

Services

  • Paid shuttle service
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's menu

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Dressing area
  • Tea and coffee facilities
  • Dining table
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock
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Dining Onsite

Lockbox offers a delightful exploration of American and local cuisines, expertly accommodating various dietary preferences such as vegetarian, vegan, gluten-free, and dairy-free. Guests are invited to indulge in a culinary experience that marries comfort and creativity within a cozy, inviting atmosphere.
21C Museum Hotel Lexington Restaurant photo

Lockbox

American, Local
Ambiance
Inviting and casual with a focus on local artistry, Lockbox provides a warm environment for relaxation and enjoyment.
Key Offerings
The menu features a range of options catering to different dietary needs, alongside unique offerings that highlight local flavors. The culinary team can also prepare a tailored catering menu for special occasions.
Reservation
Required
Open for breakfast and dinner. Breakfast: Wednesday to Saturday, 7:00 AM - 11:00 AM; Dinner: Wednesday to Thursday, 5:00 PM - 10:00 PM; Friday, 5:00 PM - 10:00 PM; Saturday, 5:00 PM - 11:00 PM; Sunday, 10:00 AM - 2:00 PM and 5:00 PM - 9:00 PM.

Location

167 West Main Street, Lexington, Kentucky, United States, 40507
Map view
167 West Main Street, Lexington, Kentucky, United States, 40507
Nearby
430 West Vine Street
Rupp Arena
460 m
Museum
Hunt-Morgan House
460 m
Event hall
Lexington Convention Center
440 m
Theatre
Kentucky Theatre
360 m
440 W Short St
Explorium
450 m
University
University of Kentucky
90 m
Park
Triangle Park
340 m
Church
St Paul the Apostle Catholic Church
430 m
Library
Lexington Public Library Ceiling Clock and Foucault Pendulum
260 m
Shopping Area
Victorian Square Shoppes
340 m
Square
Phoenix Park
180 m
Gallery
Limestone Blue
130 m
Lexington Financial Center
Isaac Murphy Memorial Art Garden
140 m
Gallery
Pam Miller Downtown Arts Center
220 m
Gallery
ArtsPlace
240 m
7285 Huron Street
Huron Street Gallery
250 m
Gratz Park
490 m
Restaurants
Bourbon on Rye
70 m
115 W Main St
Corto Lima
180 m
101 West Short Street Corner of West Short and North Limestone Streets
School Sushi
120 m
163 West Short Street
Bluegrass Tavern
150 m
115 Cheapside
Horse And Jockey
190 m
131 Cheapside
Buddha Lounge
190 m
109 N Mill St
Explore Lexington
Experience Lexington
Top Attractions
Activities
Dining
Entertainment
Mary Todd Lincoln House
Mary Todd Lincoln House
9 minutes' walk
Historic site and childhood home of Mary Todd Lincoln, showcasing Lincoln family memorabilia and guided tours available.
Rupp Arena
Rupp Arena
6 minutes' walk
Multi-purpose arena hosting sports events, concerts, and shows, notable for its vibrant ambiance and large capacity.
Lexington Cemetery
Lexington Cemetery
4 minutes' drive
Beautifully landscaped cemetery with rich history, featuring notable figures and serene pathways for reflection.
University of Kentucky Art Museum
University of Kentucky Art Museum
13 minutes' walk
Art museum featuring collections from various periods, often hosting free admission days and special events.
Horse Country Tours
12 minutes' walk
Guided tours of horse farms showcasing thoroughbreds; perfect for horse enthusiasts looking for an authentic Kentucky experience.
McConnell Springs Park
5 minutes' drive
Nature park featuring trails and historical sites, ideal for hiking and relaxing in a beautiful outdoor setting.
Bourbon on Rye
Bourbon on Rye
1 minute' walk
Local favorite known for its craft cocktails and modern twist on Southern cuisine in a casual, stylish setting.
Corto Lima
Corto Lima
3 minutes' walk
Vibrant eatery serving Latin-inspired dishes, with a focus on fresh ingredients and creative flavors; reservations recommended.
Kentucky Theatre
Kentucky Theatre
5 minutes' walk
Historic theatre showcasing indie films, classic movies, and live performances; a great spot for all ages.
Manchester Music Hall
Manchester Music Hall
15 minutes' walk
Popular venue for live music and events, known for its lively atmosphere and featuring various artists throughout the year.
Getting around
City Centre
Lexington5 min  ·  400 m
Airports
Blue Grass Airport (LEX)21 min  ·  13.7 km
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in public areas for free.
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Number of floors:
15
Number of rooms:
85
FAQs
About 21C Museum Hotel Lexington
What are the check-in and check-out times at 21C Museum Hotel Lexington?
Check-in is at 16:00 and check-out is by 11:00.
What fitness facilities are available at 21C Museum Hotel Lexington?
Guests have access to a fitness center and yoga classes.
What are the dining options at 21C Museum Hotel Lexington?
The hotel features on-site dining at Lockbox restaurant and a bar/lounge area.
Which nearby attractions are within walking distance of 21C Museum Hotel Lexington?
Nearby attractions include Rupp Arena (0.5 km) and the Lexington Convention Center (0.5 km).
What amenities do the rooms at 21C Museum Hotel Lexington offer?
Rooms include air conditioning, a flat-screen TV, a desk, and a private bathroom.
Is there a business center available at 21C Museum Hotel Lexington?
The hotel features a business center for guests needing business services.
What is the closest airport to 21C Museum Hotel Lexington?
The hotel is located 9 km from Blue Grass Airport.
What room views are available at 21C Museum Hotel Lexington?
Certain rooms offer views of the city.
Are there any children's menu options at 21C Museum Hotel Lexington?
A children's menu is available at the on-site restaurant.
What recreational opportunities are available for guests at 21C Museum Hotel Lexington?
Guests can participate in temporary art galleries, local culture tours, and walking tours.
Where can I find nearby restaurants while staying at 21C Museum Hotel Lexington?
Nearby restaurants include Infinity (0.5 km), Nat's (0.5 km), and Dudley's On Short (0.5 km).

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