Book on our site
Up to 10% cheaper
than Booking.com
Check rooms and rates
From166US$ /night
Check-in
23Nov2025Select date
Check-out
24Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
-
Close to Falls Park

Location

Home2 Suites By Hilton Sioux Falls Sanford Medical Center is situated adjacent to Sanford Medical Center, connected by a climate-controlled skywalk. The hotel is just a five-minute walk from the University of Sioux Falls and half a mile from Augustana College. This central location provides easy access to downtown Sioux Falls and local attractions.

Rooms

The hotel offers all-suite accommodations with fully equipped kitchens that include full-size refrigerators. Guest suites provide a blend of space and functionality, with options for connecting rooms available. Each room is designed to meet the diverse needs of travelers.

Wellness

Home2 Suites features an indoor pool, allowing guests to relax or swim regardless of the weather. The hot tub provides a comforting space for unwinding after a day of exploring. These wellness facilities contribute to a balanced travel experience.

Dining

The hotel includes a complimentary hot breakfast buffet, available each morning to energize guests for the day. Guests appreciate the convenience of dining options without having to venture far. Additionally, kitchens in the suites enable in-room meal preparation.

Pet-Friendly Amenities

Home2 Suites accommodates pets with designated pet-friendly rooms and applicable fees. Guests can stay with up to two pets, making travel more convenient. This policy reflects the hotel's commitment to serving a wider range of visitors.

Highlights

Location: connected to Sanford Medical Center via climate-controlled skywalk

Rooms: all-suite accommodations with fully equipped kitchens

Wellness: indoor pool & hot tub

Dining: complimentary hot breakfast buffet

Must-do experiences

  • Visit the Sioux Falls SculptureWalk for stunning public art.
  • Try the bison burger at Falls Overlook Cafe for a local favorite.
  • Take a stroll at Falls Park to see the beautiful waterfalls.
  • Check out the Washington Pavilion for arts and science exhibits.
  • Explore the local flavors at the Sioux Falls Farmers Market on Saturday.
View all

Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
King Studio Suite Non-Smoking
2 persons
40 m² 
1 King-size bed
Heating
Air conditioning
Queen Studio Two Queen Beds Non-Smoking
2 persons
40 m² 
2 King Size Beds
Heating
Air conditioning
King Studio Suite Hearing Access or Non-Smoking
2 persons
40 m² 
1 King-size bed
Heating
Air conditioning
Queen Studio Two Queen Beds Mobility Access or Non-Smoking
2 persons
40 m² 
2 King Size Beds
Heating
Air conditioning
Click button to see more rooms
Show all rooms
Show all roomsLess

Price and Room Availability Calendar

Check availability and prices for your dates now!

Getting around

A list of all available modes of transport

City Centre
Sioux Falls800 m
Airports
Sioux Falls Regional (FSD) 7.9 km
Stronsay (soy) 86.3 km

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Free Wi-Fi
  • Free parking
  • Off-site car park
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift

Sports & Fitness

  • Fitness centre

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Spa & Leisure

  • Indoor swimming pool
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
Show more

Location

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Map view
1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Nearby
1305 W 18th St In the Sanford USD Medical Center
Sioux Empire Medical Museum
290 m
1001 SW Avenue
Sioux Falls Stadium
530 m
Restaurants
The Co-op of Sioux Falls
860 m
410 W 18th St
Azteca
1.1 km
811 S Minnesota Ave
Toppers Pizza
1.1 km
817 S Minnesota Ave
Taco John's
1.0 km
1100 S Minnesota Ave
Papa John's Pizza
1.1 km
711 S Minnesota Ave
Abelardo's Mexican Food
1.1 km
1200 S Minnesota Ave
Pho Quynh
960 m
1100 W 12th St
Want to see Exclusive Early Booking Rate?
Get exlusive rates right now!
Check Rates
FAQs
About Home2 Suites By Hilton Sioux Falls Sanford Medical Center
Check-in
23Nov2025Select date
Check-out
24Nov2025Select date
Rooms and Guests2 Guests, 1 Room