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From169US$ /night
Check-in
25Feb2026Select date
Check-out
26Feb2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4250 Midamerica Lane, Mehlville, Missouri, United States
-
Near Sylvan Springs County Park
Perfect
9.2
9.4
/10
4.4
4.4
/5

Amenities

Holiday Inn Express & Suites - St. Louis South - I-55 offers an indoor heated pool and an outdoor guest patio with a fire pit for relaxation. The hotel features a complimentary business center, ensuring that guests can handle their work needs efficiently. Nightly cookies and milk are provided for an enjoyable treat after a long day.

Rooms

The hotel provides 99 guest rooms, including 17 suites designed to accommodate both business and leisure travelers. Each room includes a 49-inch HD TV, a fridge, a microwave, and a Keurig brewer for convenience. Enhanced bath experiences with curved shower rods are also available to enhance guest comfort.

Location

Located in Mehlville, the hotel is close to Downtown St. Louis and the iconic Gateway Arch. Guests can easily access nearby attractions like the River City Casino, which features updated dining options. The updated Arch Grounds provides opportunities for walking and exploring the area around the riverfront.

Dining

Holiday Inn Express & Suites offers a complimentary Express Start Breakfast including a variety of hot and fresh options. Guests can enjoy favorites such as egg white omelets, turkey sausage, and the hotel's famous cinnamon rolls each morning. Coffee is provided free in the lobby throughout the day.

Business Services

The hotel includes two meeting rooms that can accommodate various small events or business functions. Equipped with audiovisual equipment, including LCD projectors, the spaces are designed for productive gatherings. A business center is available for guest use and includes basic office supplies.

Highlights

Location: Close to Downtown St. Louis and the Gateway Arch

Rooms: 99 guest rooms and 17 suites with triple-sheeted bedding

Ample Parking: Complimentary self-parking available

Dining: Complimentary Express Start Breakfast with hot favorites

Must-do experiences

  • Visit Grants Farm to see the amazing wildlife and enjoy a cold beer.
  • Taste toasted ravioli at the iconic St. Louis Italian restaurant, Mama's.
  • Check out the Historic Route 66 at Ted Drewes for famous frozen custard.
  • Stroll through Tower Grove Park and take in its stunning historic pavilions.
  • Explore the City Museum for an unforgettable art and play experience.
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Select your room type

Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Standard Room Two Queen Beds
2 persons
305 sq. feet 
2 King Size Beds
Heating
Air conditioning
Deluxe King Room
2 persons
305 sq. feet 
1 King-size bed and 1 Sofa bed
Heating
Air conditioning
Suite
2 persons
305 sq. feet 
2 King Size Beds
Heating
Air conditioning
Standard Double Suite
2 persons
305 sq. feet 
1 King-size bed and 1 Sofa bed
Heating
Air conditioning
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Facilities

Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg offers amenities for your comfortable stay and unforgettable experiences
Facilities: Perfect
9.3/10Review score

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Lift
  • Vending machines
  • Smoke detectors
  • Fire extinguishers

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's buffet
  • Toys

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Sun loungers

Room features

  • Air conditioning
  • Heating
  • Garden furniture

Media

  • Flat-screen TV
  • AM/FM alarm clock
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Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg Location

4250 Midamerica Lane, Mehlville, Missouri, United States
Map view
4250 Midamerica Lane, Mehlville, Missouri, United States
Nearby
Assembly of God South Side Church
600 ft
Saint Louis College of Health
1900 ft
Restaurants
Taco Bell
1700 ft
4320 Butler Hill Road
Burger King
1600 ft
4324 Butler Hill Rd
Soulard Gyro
2100 ft
4337 Butler Hill Rd
Panda
1900 ft
4337 Butler Hill Rd Ste E
Explore Mehlville
Explore the Local Scene
Top Attractions
Activities
Dining
Entertainment
Missouri Civil War Museum
Missouri Civil War Museum
15-minute drive
Civil War history exhibits and artifacts showcasing Missouri's role in the conflict. Guided tours available.
Clydesdale Park
6-minute drive
Sprawling park offering walking trails, playgrounds, and picnic areas. Ideal for families and outdoor enthusiasts.
Keller Plaza 8
25-minute walk
Local movie theater featuring the latest films with comfortable seating and a cozy vibe for casual outings.
Tee Time Family Fun Center
5-minute drive
Family entertainment center with mini-golf, arcade games, and more. Perfect for kids and family bonding.
Outdoor Hiking at Clydesdale Park
6-minute drive
Scenic trails for hiking and jogging with beautiful nature views. Great for outdoor enthusiasts seeking adventure.
Mini-Golf at Tee Time Family Fun Center
5-minute drive
Fun-filled mini-golf course suitable for all ages. No previous booking necessary, just walk in and enjoy!
Relaxing at Local Spas
10-minute drive
Spas offering massages and wellness treatments, perfect for a relaxing day away. Reservation recommended.
Soulard Gyro
Soulard Gyro
8-minute walk
Casual eatery specializing in Mediterranean flavors, with signature gyros and vegetarian options. Cozy atmosphere.
Panda
Panda
7-minute walk
Chinese cuisine with a variety of dishes, known for quick service and takeout. Vegetarian options available.
Burger King
Burger King
6-minute walk
Fast food classic with flame-grilled burgers and a casual dining experience. Ideal for a quick meal.
Keller Plaza 8 Theater
25-minute walk
Catch the latest movies in a relaxed setting. Offers special screenings and promotions for movie lovers.
BounceU of St. Louis
BounceU of St. Louis
10-minute drive
Indoor inflatable play center perfect for family fun. Offers themed bounce parties and family-friendly activities.
Getting around
City Centre
Mehlville3 min  ·  700 ft
Airports
St. Louis Lambert International Airport (STL)63 min  ·  25.9 mi
Belleville, IL (BLV)95 min  ·  39.2 mi
Train
Shrewsbury Metrolink Station19 min  ·  7.7 mi
Sunnen Metrolink Station21 min  ·  8.6 mi
Bus
Bus stop5 min  ·  1400 ft
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
is available in for free.
Breakfast
The hotel Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg provides visitors with a free full breakfast. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are not allowed.
Number of floors:
4
Number of rooms:
104
Former name
holiday inn express & suites - st. louis south - i-55, an ihg hotel

Reviews and Ratings

Feedback about Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg from previous guests about their experience.
Review score
Based on 173 verified reviews
9.4/10
Perfect
96%
Recommend
Cleanliness
9.3/10
Comfort
9.4/10
Facilities
9.3/10
Free Wi-Fi
9.5/10
Location
9.4/10
Paid Wi-Fi
7.4/10
Staff
9.5/10
Value for money
9.0/10
Guest reviews
based on 107 reviews
9.2/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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FAQs
About Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg
What is the check-in and check-out policy at Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg?
Check-in is at 15:00 and check-out is by 11:00.
Does Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg have a swimming pool?
The hotel features an indoor heated pool that is open year-round.
What room amenities are provided at Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg?
Rooms include air conditioning, a flat-screen TV, a refrigerator, and a desk.
How far is Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg from the St. Louis Gateway Arch?
The hotel is located 24 km from the St. Louis Gateway Arch.
What breakfast options does Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg offer?
Guests can enjoy a free Express Start Breakfast with diverse selections.
Are there dining options available on-site at Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg?
The hotel features an on-site restaurant that serves breakfast and supper.
Is there a fitness center at Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg?
Yes, the hotel has a fitness center equipped with modern workout equipment.
What are some features of the business facilities at Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg?
The hotel offers a business center and two meeting rooms suitable for business functions.
Which languages are spoken by staff at Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg?
The staff primarily speaks English.
How far is Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg from St. Louis Lambert International Airport?
The hotel is 33 km from St. Louis Lambert International Airport.
What is a notable nearby restaurant to Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg?
Frailey's Southtown Grill is located 0.5 km from the hotel.
What entertainment options for children are available at Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg?
The hotel provides swimming pool toys and a children's buffet.

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Check-in
25Feb2026Select date
Check-out
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Rooms and Guests2 Guests, 1 Room

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Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg Mehlville Exterior photo

Holiday Inn Express & Suites - St. Louis South - I-55 By Ihg

9.2
Perfect107 reviews
700 ft from center
152 US$
169 US$
per night
Mobile-only price