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From70US$ /night
Check-in
25Nov2025Select date
Check-out
26Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4600 I-40 E, Amarillo, Texas, United States, 79103-6200
-
Close to Splash Amarillo
Perfect
8.6
9.1
/10
4.2
/5

Amenities

Best Western Santa Fe offers a 24-hour front desk and laundry facilities for guest convenience. It includes an outdoor pool open seasonally, providing an option to relax under the Amarillo sun. Guests can also access the hotel's fitness center for an invigorating workout.

Rooms

The hotel features a variety of room types, including standard and upgraded accommodations equipped with a microwave and refrigerator. Spacious suites add a living area, offering extra space for relaxation. Select rooms provide easy access for those with mobility needs.

Location

Located off Interstate 40, Best Western Santa Fe provides easy access to popular local attractions such as the Route 66 Historic District. The hotel is also a short drive from the Amarillo Zoo and Panhandle-Plains Historical Museum. The proximity to local dining options adds convenience for guests.

Business Facilities

The hotel offers a business center equipped with essential services to meet business travelers' needs. Meeting rooms are available for small gatherings and presentations. The hotel's convenient location allows easy access to local businesses.

Dining

Guests can enjoy a complimentary hot breakfast buffet each morning, offering a selection to start the day right. The hotel is situated near various dining options, providing guests with diverse choices for meals. Local favorites and traditional American fare are just a short walk away.

Highlights

Location: Conveniently located off Interstate 40

Dining: Complimentary hot breakfast buffet

Amenities: Outdoor pool and fitness center

Business: Business center with essential services

Must-do experiences

  • Visit Cadillac Ranch to see vibrant art and leave your mark.
  • Try the 72 oz. steak challenge at The Big Texan Steak Ranch.
  • Explore the historic Route 66 district for unique shops and diners.
  • Check out the American Quarter Horse Hall of Fame & Museum.
  • Join a local ghost tour to hear Amarillo's spooky stories.
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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
King Room Pet-Friendly or Non-Smoking
2 persons
19 m² 
1 King-size bed
Air conditioning
Queen Room Two Queen Beds Pet-Friendly or Non-Smoking
2 persons
19 m² 
2 King Size Beds
Air conditioning
Queen Room Disability Access
2 persons
19 m² 
1 King-size bed
Air conditioning
Queen Room Two Queen Beds Disability Access or Non-Smoking
2 persons
19 m² 
2 King Size Beds
Air conditioning
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Getting around

A list of all available modes of transport

City Centre
Amarillo 5.6 km
Airports
Rick Husband Amarillo International (AMA) 9.3 km

Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Internet access
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Vending machines
  • Smoke detectors
  • Fire extinguishers

Sports & Fitness

  • Golf course

Guest Parking

  • Dryer

Services

  • Housekeeping
  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Seasonal outdoor pool
  • Heated swimming pool
  • Beach umbrellas
  • Sun loungers

Room features

  • Free Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Dining table
  • Ironing facilities

Bathroom

  • Washing machine
  • Free toiletries

Self-catering

  • Dryer

Media

  • Flat-screen TV
  • Direct dial telephone
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Location

4600 I-40 E, Amarillo, Texas, United States, 79103-6200
Map view
4600 I-40 E, Amarillo, Texas, United States, 79103-6200
Nearby
1415 Sunrise Dr
Splash Amarillo
1.0 km
1415 Sunrise Dr
Starlight Ranch Event Center
1.1 km
Restaurants
El Charro Mexican Food
580 m
4207 I-40 East
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FAQs
About Best Western Santa Fe
Check-in
25Nov2025Select date
Check-out
26Nov2025Select date
Rooms and Guests2 Guests, 1 Room