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From70US$ /night
Check-in
11Jan2026Select date
Check-out
12Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4600 I-40 E, Amarillo, Texas, United States, 79103-6200
-
Close to Splash Amarillo
Great
8.5
9.0
/10
4.2
/5

Amenities

Best Western Santa Fe offers a 24-hour front desk and laundry facilities for guest convenience. It includes an outdoor pool open seasonally, providing an option to relax under the Amarillo sun. Guests can also access the hotel's fitness center for an invigorating workout.

Rooms

The hotel features a variety of room types, including standard and upgraded accommodations equipped with a microwave and refrigerator. Spacious suites add a living area, offering extra space for relaxation. Select rooms provide easy access for those with mobility needs.

Location

Located off Interstate 40, Best Western Santa Fe provides easy access to popular local attractions such as the Route 66 Historic District. The hotel is also a short drive from the Amarillo Zoo and Panhandle-Plains Historical Museum. The proximity to local dining options adds convenience for guests.

Business Facilities

The hotel offers a business center equipped with essential services to meet business travelers' needs. Meeting rooms are available for small gatherings and presentations. The hotel's convenient location allows easy access to local businesses.

Dining

Guests can enjoy a complimentary hot breakfast buffet each morning, offering a selection to start the day right. The hotel is situated near various dining options, providing guests with diverse choices for meals. Local favorites and traditional American fare are just a short walk away.

Highlights

Location: Conveniently located off Interstate 40

Dining: Complimentary hot breakfast buffet

Amenities: Outdoor pool and fitness center

Business: Business center with essential services

Must-do experiences

  • Visit Cadillac Ranch to see vibrant art and leave your mark.
  • Try the 72 oz. steak challenge at The Big Texan Steak Ranch.
  • Explore the historic Route 66 district for unique shops and diners.
  • Check out the American Quarter Horse Hall of Fame & Museum.
  • Join a local ghost tour to hear Amarillo's spooky stories.
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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
King Room Pet-Friendly or Non-Smoking
2 persons
19 m² 
1 King-size bed
Air conditioning
Queen Room Two Queen Beds Pet-Friendly or Non-Smoking
2 persons
19 m² 
2 King Size Beds
Air conditioning
Queen Room Disability Access
2 persons
19 m² 
1 King-size bed
Air conditioning
Queen Room Two Queen Beds Disability Access or Non-Smoking
2 persons
19 m² 
2 King Size Beds
Air conditioning
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Price and Room Availability Calendar

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Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Internet access
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Vending machines
  • Smoke detectors
  • Fire extinguishers

Sports & Fitness

  • Golf course

Services

  • Housekeeping
  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Seasonal outdoor pool
  • Heated swimming pool
  • Beach umbrellas
  • Sun loungers

Room features

  • Air conditioning
  • Heating
  • Tea and coffee facilities
  • Ironing facilities

Media

  • AM/FM alarm clock
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Location

4600 I-40 E, Amarillo, Texas, United States, 79103-6200
Map view
4600 I-40 E, Amarillo, Texas, United States, 79103-6200
Nearby
1415 Sunrise Dr
Splash Amarillo
1.0 km
1415 Sunrise Dr
Starlight Ranch Event Center
1.1 km
Restaurants
El Charro Mexican Food
580 m
4207 I-40 East
Explore Amarillo
Explore Amarillo
Top Attractions
Activities
Dining
Entertainment
American Quarter Horse Museum
American Quarter Horse Museum
5-minute drive
Showcases the history and significance of the American Quarter Horse. Features exhibits and events for horse enthusiasts.
Splash Amarillo
Splash Amarillo
5-minute drive
Family-friendly water park with slides, lazy rivers, and play areas. Perfect for a summer day of fun and relaxation.
Benton Park
13 minutes' walk
A community park with playgrounds, walking trails, and picnic areas. Great for families seeking outdoor activities.
Firewater Water Park
15 minutes' walk
Water park featuring thrilling slides and splash pools. A go-to for thrill-seekers and families alike.
Mike's Amusement
15 minutes' walk
Amusement center with arcade games and rides. Ideal for solo travelers and families seeking entertainment.
El Charro Mexican Food
El Charro Mexican Food
7 minutes' walk
Casual eatery known for flavorful Mexican dishes. Favorites include tacos and enchiladas; vegetarian options available.
Grand Palace Amusement
5-minute drive
Family-friendly venue offering food and fun. Known for its pizza, burgers, and vibrant atmosphere.
Tri-State Exposition
20 minutes' walk
Hosts various events including fairs and rodeos. A lively spot for families and groups to enjoy entertainment.
Amarillo Dillas Pro Baseball
20 minutes' walk
Local baseball team with games offering a fun outing for sports fans. Family-friendly atmosphere with concessions.
Getting around
City Centre
Amarillo9 min  ·  5.6 km
Airports
Rick Husband Amarillo International Airport (AMA)14 min  ·  9.3 km
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible at a location nearby for free.
Internet
High-speed internet access is available in public areas for free.
Breakfast
A american breakfast is served at affordable prices. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Number of rooms:
56
FAQs
About Best Western Santa Fe
What is the distance from Best Western Santa Fe to Rick Husband Amarillo International Airport?
The hotel is located 5 km from Rick Husband Amarillo International Airport, approximately a 15-minute drive.
Which popular attractions are close to Best Western Santa Fe?
Nearby attractions include the American Quarter Horse Hall of Fame & Museum (5 km), Amarillo Botanical Gardens (7 km), and Big Texan Steak Ranch (2 km).
What are some of the amenities offered at Best Western Santa Fe?
Amenities include a seasonal outdoor swimming pool, business center, laundry facilities, free Wi-Fi, and 24-hour front desk services.
What type of breakfast is served at Best Western Santa Fe?
A complimentary full hot breakfast is served daily from 6 AM, featuring Texas-shaped waffles, cereals, yogurt, and pastries.
Is there parking available at Best Western Santa Fe?
Public parking is available nearby for free on a first-come, first-served basis.
What room amenities can guests expect at Best Western Santa Fe?
Rooms are equipped with air conditioning, a refrigerator, a flat-screen TV, and complimentary Wi-Fi.
Does Best Western Santa Fe allow pets?
Pets are allowed at the hotel, with possible additional charges.
What are the check-in and check-out times at Best Western Santa Fe?
Check-in is at 15:00 and check-out is by 11:00.
Does Best Western Santa Fe offer any business services?
The hotel features a business center with corporate-friendly facilities and free Wi-Fi.
What recreational activities are available at Best Western Santa Fe?
Guests can enjoy access to a seasonal outdoor pool and a golf course for recreation.
How far is Best Western Santa Fe from the city center?
The hotel is approximately 8 km from the city center of Amarillo.
What dining options are available near Best Western Santa Fe?
Nearby dining options include the Big Texan Steak Ranch (2 km), known for its steak challenges.

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