Comfort Inn & Suites Chillicothe Exterior photoComfort Inn & Suites Chillicothe Exterior photoComfort Inn & Suites Chillicothe Exterior photo
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From109US$ /night
Check-in
19Apr2026Select date
Check-out
20Apr2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

250 Business 36, Chillicothe, Missouri, United States, 64601
-
Close to Chillicothe Main Street
Great
8.8
/10
4.6
/5

Accommodations

Comfort Inn & Suites Chillicothe offers 75 spacious rooms, designed for both business and leisure travelers. Each room includes a refrigerator and microwave, providing convenience for guests on-the-go. The hotel also features whirlpool suites that enhance guest experiences for relaxation.

Dining

The hotel provides a fresh and free hot breakfast each morning, featuring options like eggs, waffles, and sausage. Guests can also find coffee available in the lobby area throughout the day. The proximity to local dining options allows guests to explore various cuisines nearby.

Business and Events

Comfort Inn & Suites Chillicothe has a well-equipped business center, making it convenient for corporate travelers. A meeting space is also available that can accommodate up to 30 guests, suitable for small gatherings or training sessions. The hotel's central location provides easy access for attendees from surrounding areas.

Location

Located just off Highway 36, this hotel provides easy access to various attractions in Chillicothe. Nearby destinations include the famous Outdoor drama 'The Gallatin', perfect for cultural enthusiasts. The hotel is also a short distance from local parks and recreational areas.

Fitness and Leisure

Guests can maintain their fitness routine at the on-site fitness center, equipped with essential workout machines. The hotel features an indoor heated pool available for guests year-round. For leisure, the outdoor patio area offers a relaxing space for unwinding after a busy day.

Highlights

Location: Just off Highway 36 for easy access

Accommodations: 75 spacious rooms with refrigerators

Dining: Fresh and free hot breakfast every morning

Business: Meeting space for up to 30 guests

Leisure: Indoor heated pool available year-round

Comforts: Whirlpool suites for enhanced relaxation

Must-do experiences

  • Visit Hopewell Culture National Historical Park for ancient earthworks.
  • Try the famous soup at the City Barbeque for a local flavor.
  • Explore the Chillicothe Paints games for a fun night out.
  • Don't miss the Ross County Historical Society for local history.
  • Take a stroll at the Yoctangee Park for beautiful scenery.
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Price and Room Availability Calendar

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Facilities

Comfort Inn & Suites Chillicothe offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Wi-Fi
  • Free parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Fire extinguishers

Sports & Fitness

  • Fitness centre
  • Hiking
  • Horseback riding
  • Tennis court
  • Bowling
  • Golf course

Guest Parking

  • Shared kitchen

Services

  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning

Business

  • Meeting/ Banquet facilities

Spa & Leisure

  • Indoor swimming pool
  • BBQ facilities
  • Leisure/ TV room
  • Spa & wellness centre
  • Sauna
  • Jacuzzi

Room features

  • Ironing facilities

Self-catering

  • Shared kitchen
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Comfort Inn & Suites Chillicothe Location

250 Business 36, Chillicothe, Missouri, United States, 64601
Map view
250 Business 36, Chillicothe, Missouri, United States, 64601
Nearby
Chillicothe Main Street
0 ft
Restaurants
China Garden
1900 ft
1023 S Washington St
McDonald's
2500 ft
810 Business Highway 36 West
Explore Chillicothe
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Chillicothe Community of Christ
5 minutes' drive
A beautiful church known for its welcoming atmosphere and community events, perfect for those seeking local culture.
Chillicothe Main Street
Chillicothe Main Street
10 minutes' drive
Historic Main Street featuring shops, art galleries, and seasonal events highlighting local history and charm.
Daryl Danner Memorial Park
10 minutes' drive
A peaceful park offering trails and picnic areas, ideal for family outings and relaxing nature walks.
Biking at Chillicothe Trails
10 minutes' drive
A scenic biking trail suitable for all levels, available for rental and fun for those seeking adventure.
Spa Services
10 minutes' drive
Local spas offering massages and wellness treatments, perfect for relaxation on a day off or after meetings.
China Garden
China Garden
7 minutes' walk
Casual eatery serving a variety of authentic Chinese dishes with vegetarian options available, family-friendly atmosphere.
McDonald's
McDonald's
10 minutes' walk
Fast food favorite offering classic burgers and fries, convenient for a quick and familiar meal any time.
Grand 6 Movie Theatre
10 minutes' drive
Multiplex cinema screening the latest films, perfect for families and couples seeking an entertaining night out.
Local Bars
10 minutes' drive
Several bars in the area featuring live music and trivia nights, great for enjoying local nightlife with friends.
Getting around
City Centre
Chillicothe30 min  ·  1.6 mi
Airports
Kirksville Regional (IRK)205 min  ·  84.7 mi
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Private parking is possible on site for free.
Internet
Wireless internet is available in for free.
Breakfast
A buffet breakfast is served and charges are applicable. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are not allowed.
Number of rooms:
72

Reviews and Ratings

Feedback about Comfort Inn & Suites Chillicothe from previous guests about their experience.
Review score
Based on 2 verified reviews
10.0/10
Perfect
100%
Recommend
Guest reviews
based on 45 reviews
8.8/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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FAQs
About Comfort Inn & Suites Chillicothe
What time is check-in and check-out at Comfort Inn & Suites Chillicothe?
Check-in is at 15:00 and check-out is at 11:00.
Is parking available at Comfort Inn & Suites Chillicothe?
Paid parking is available on-site for guests.
What are some amenities offered at Comfort Inn & Suites Chillicothe?
Amenities include free Wi-Fi, an indoor heated pool, a fitness center, and a 24-hour business center.
What are the room amenities at Comfort Inn & Suites Chillicothe?
Rooms are equipped with air conditioning, flat-screen TVs, microwaves, refrigerators, coffee makers, and private bathrooms.
What kind of breakfast is served at Comfort Inn & Suites Chillicothe?
The hotel offers a free hot breakfast featuring eggs, meat, yogurt, fresh fruit, and a variety of waffle flavors.
Are there nearby attractions to Comfort Inn & Suites Chillicothe?
Nearby attractions include Poosey State Forest (9 km), Chillicothe Country Club (4 km), and Pershing State Park (18 km).
What dining options are available near Comfort Inn & Suites Chillicothe?
China Garden is located 0.5 km from the hotel.
What recreational activities can guests enjoy at Comfort Inn & Suites Chillicothe?
Guests can engage in activities such as hiking, horseback riding, bowling, and golfing.
Is there a shared kitchen at Comfort Inn & Suites Chillicothe?
Yes, a shared kitchen is available for guest use.
How far is Comfort Inn & Suites Chillicothe from Kirksville Regional Airport?
The hotel is located 100 km from Kirksville Regional Airport.
What business services are offered at Comfort Inn & Suites Chillicothe?
The hotel provides a business center, complimentary newspapers in the lobby, and high-speed Wi-Fi.

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Check-in
19Apr2026Select date
Check-out
20Apr2026Select date
Rooms and Guests2 Guests, 1 Room