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From125US$ /night
Check-in
09Jan2026Select date
Check-out
10Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

201 North Main Street, Hannibal, Missouri, United States, 63401
-
Just steps from Bluff City Theater
Perfect
9.0
/10
4.6
/5

Location

Main Street Bed & Breakfast is located in Hannibal, steps from attractions along the Mississippi River. Guests can explore the nearby Mark Twain Boyhood Home and Museum, as well as the Mark Twain Memorial Lighthouse. The accommodation is also within walking distance of various shops and dining options.

Rooms

The bed and breakfast offers spacious rooms that come equipped with necessary amenities for a comfortable stay. Each room reflects the character of the historic building and provides access to large bathrooms. Guests can find various room options, including the Safari Room, tailored to their preferences.

Dining

A complimentary continental breakfast is included with every stay, offering a convenient start to the day. Snacks and beverages are also provided to ensure guests have ample refreshment. Local restaurants and bars are just a short walk from the hotel.

Entertainment

Main Street Bed & Breakfast is conveniently located near several local theaters, including Planters Barn Theater and Bluff City Theater. Outdoor enthusiasts can enjoy kayaking and fishing opportunities in close proximity. Cycling and mountain biking routes are available nearby for those seeking adventure.

Parking

The hotel provides free parking, allowing guests to easily explore the area without hassle. Self-check-in is available after 8 PM for added convenience. This feature makes it easy for guests traveling at different hours to check in comfortably.

Highlights

Location: Steps from attractions along the Mississippi River

Dining: Complimentary continental breakfast

Entertainment: Nearby local theaters and outdoor activities

Parking: Free parking and self check-in available

Must-do experiences

  • Visit the Mark Twain Boyhood Home for a literary journey.
  • Savor a slice of the famous Huck Finn pie at the Pie Pantry.
  • Explore the scenic views at Lover's Leap Park at sunset.
  • Don't miss the Hannibal History Museum for local tales.
  • Take a riverboat cruise on the Mississippi for stunning sights.
View all

Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Deluxe Queen Suite
2 persons
37 m² 
1 King-size bed
Shower
Coffee machine
Deluxe King Suite
2 persons
41 m² 
1 King-size bed
Shower
Coffee machine

Price and Room Availability Calendar

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Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • VIP check-in/ -out
  • Express check-in/ -out
  • Concierge desk
  • No pets allowed
  • Security
  • Adults only
  • Smoke detectors
  • Fire extinguishers
  • Key access

Sports & Fitness

  • Canoeing
  • Hiking
  • Cycling
  • Bowling
  • Golf course
  • Fishing

Services

  • Valet parking
  • Housekeeping
  • Tours/Ticket assistance

Dining

  • In-room breakfast
  • Special diet menus

Spa & Leisure

  • Aqua park
  • Live entertainment
  • Night club
  • BBQ facilities
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Garden furniture
  • Tea and coffee facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
Show more

Location

201 North Main Street, Hannibal, Missouri, United States, 63401
Map view
201 North Main Street, Hannibal, Missouri, United States, 63401
Nearby
Museum
Mark Twain Boyhood Home and Museum
400 m
Bridge
Mark Twain Memorial Lighthouse
400 m
Hannibal
Tom and Huck's Statue
400 m
Museum
Jim's Journey
400 m
211 Hill St
Haunted House on Hill Street Wax Museum
220 m
Hannibal
Becky Thatcher's House
400 m
114 S 3rd St
Karlocks Kars and Pop Culture Museum
310 m
320 N 3rd St
Big River Train Town
400 m
600 Butler St
Molly Brown Museum and Home
400 m
Library
Hannibal Free Public Library
530 m
Park
Glascock's Landing
400 m
162-198 North St
Tom Sawyer and Huck Finn Statue
310 m
320 Broadway
Hannibal Parks & Recreation
320 m
Museum
Hannibal History Museum
400 m
600 Butler St
Molly Brown Birthplace
400 m
Store
Bluff City Theatre
400 m
Restaurants
The Brick Oven
10 m
207 Center Street
Java Jive
40 m
211 N Main St
Finn's Food and Spirits
50 m
214 N Main St
Chocolaterie Stam
80 m
103 N Main St
Riverside Restaurant
160 m
111 Bird St
Mark Twain Dinette
330 m
400 N 3rd St
Explore Hannibal
Activities, Dining & Entertainment
Top Attractions
Activities
Dining
Entertainment
Mark Twain Boyhood Home and Museum
Mark Twain Boyhood Home and Museum
5 minutes' walk
Mark Twain's literary heritage showcased with exhibits and guided tours. A must-visit for literature enthusiasts.
Haunted House on Hill Street Wax Museum
Haunted House on Hill Street Wax Museum
3 minutes' walk
A captivating wax museum featuring eerie figures and local lore. Family-friendly and perfect for curious visitors.
Lovers Leap
19 minutes' walk
A scenic overlook with breathtaking views of the Mississippi River. Ideal for romantic moments or photography.
Rockcliffe Mansion
Rockcliffe Mansion
18 minutes' walk
A historic mansion offering guided tours that delve into its Victorian architecture and intriguing history.
Hiking at Sodalis Nature Preserve
25 minutes' walk
Trail systems through diverse habitats. Perfect for hiking, birdwatching, or enjoying nature's tranquility.
Mark Twain Cave Tours
6 minutes' drive
Explore the iconic cave with guided tours highlighting its geological features and Twain's history here.
Biking along the Riverfront Trail
5 minutes' drive
A scenic biking route alongside the river. Rentals available nearby to enjoy outdoor activity.
Yoga at Riverside Park
2 minutes' walk
Relaxing outdoor yoga sessions offered seasonally, ideal for unwinding amidst nature.
The Brick Oven
The Brick Oven
1 minute' walk
Quaint pizzeria with a cozy ambiance and a variety of specialty pizzas and local brews.
Finn's Food and Spirits
Finn's Food and Spirits
1 minute' walk
Casual dining with comfort food and a full bar. Known for its burgers and friendly atmosphere.
Riverside Restaurant
Riverside Restaurant
2 minutes' walk
Riverside views complement an extensive menu featuring local fare. Reservations recommended for peak hours.
Java Jive
Java Jive
1 minute' walk
Charming café known for its artisanal coffee and delectable pastries. Great for breakfast or a coffee break.
Riverland Theatre
5 minutes' drive
Local arts theater showcasing live performances and indie films. A great choice for evening entertainment.
The Gold Bar
2 minutes' walk
Lively bar with live music and trivia nights, creating a fun atmosphere for both locals and visitors.
Mark Twain Riverboat
10 minutes' walk
Experience the Mississippi River with scenic boat rides. Unique entertainment options include dinner cruises.
Hannibal History Museum
10 minutes' walk
Family-friendly museum featuring exhibits on Hannibal's history, including Twain memorabilia and events.
Getting around
City Centre
Hannibal5 min  ·  400 m
Airports
Quincy Regional Airport (UIN)68 min  ·  44.8 km
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Property information and rules
Check-in
from 14:00-20:00
Check-out
from 06:00-11:00
Guest Parking
Private parking is possible on site for free.
Internet
is available in for free.
Breakfast
At the hotel Main Street Bed & Breakfast guests are invited to a full breakfast served for free. 
Pets
Pets are not allowed.
FAQs
About Main Street Bed & Breakfast
How far is Main Street Bed & Breakfast from Quincy Regional Airport?
Main Street Bed & Breakfast is 45 km from Quincy Regional Airport.
What time is check-in and check-out at Main Street Bed & Breakfast?
Check-in is at 14:00 and check-out is at 11:00.
What types of activities can guests enjoy at Main Street Bed & Breakfast?
Guests can enjoy activities such as cycling, fishing, hiking, and walking tours.
Is parking available at Main Street Bed & Breakfast?
Free private parking is available on-site, without the need for a reservation.
What dining options are available at Main Street Bed & Breakfast?
The hotel offers a continental breakfast daily, with breakfast in the room also available.
How close is Main Street Bed & Breakfast to nearby attractions like the Mark Twain Boyhood Home and Museum?
Main Street Bed & Breakfast is 0.5 km from the Mark Twain Boyhood Home and Museum.
What room amenities are offered at Main Street Bed & Breakfast?
Rooms include air conditioning, a flat-screen TV, a fridge, and a coffee machine.
Does Main Street Bed & Breakfast have any spa facilities?
Guests can enjoy a hot tub and spa bath in their rooms.
What languages do the staff at Main Street Bed & Breakfast speak?
Staff members are available to assist guests in English.
What recreational facilities are available for guests at Main Street Bed & Breakfast?
The hotel offers bike hire for guests to explore the area.
Which nearby restaurants can guests find while staying at Main Street Bed & Breakfast?
Nearby restaurants include Rumor Has IT, Java Jive, Finn's Food and Spirits, Due Amici Pizzeria, and Mark Twain Dinette, all within 0.5 km.

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