Main Street Bed & Breakfast Hannibal Exterior photoMain Street Bed & Breakfast Hannibal Exterior photoMain Street Bed & Breakfast Hannibal Beds photo
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From125US$ /night
Check-in
19Apr2026Select date
Check-out
20Apr2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

201 North Main Street, Hannibal, Missouri, United States, 63401
-
Just steps from Bluff City Theater
Perfect
9.2
/10
4.4
/5

Location

Main Street Bed & Breakfast is situated just steps away from the banks of the Mighty Mississippi. The hotel is within walking distance of iconic landmarks, including the Mark Twain Boyhood Home and Museum. Guests can explore local theaters such as Planters Barn Theater and Bluff City Theater, adding cultural charm to their visit.

Dining

The hotel offers a complimentary breakfast each morning, along with snacks and beverages throughout the day. Local dining options abound, with a variety of restaurants and cafes just a short walk away. Guests can enjoy the convenience of being close to dining while savoring fresh baked goods and beverages at the hotel.

Amenities

Main Street Bed & Breakfast provides free parking for guests, making travel easier during stays. Self check-in is available after 8 PM, allowing flexibility for late arrivals. The property also showcases spacious rooms that are accessible for visitors to unwind after a day of exploration.

Activities

Outdoor enthusiasts can take advantage of nearby activities such as kayaking and fishing in the Mississippi River. The surrounding area also offers opportunities for mountain biking and cycling. Local attractions like Big River Train Town enhance the adventure experience in Hannibal.

Rooms

Rooms at Main Street Bed & Breakfast are spacious, designed to accommodate travelers seeking comfort and convenience. Each room offers essential amenities to ensure a relaxing stay. Its historical charm is evident throughout the property, adding a unique character to the guest experience.

Highlights

Location: Steps away from the Mighty Mississippi

Dining: Complimentary breakfast, snacks, and beverages

Amenities: Free parking available

Activities: Kayaking and fishing opportunities nearby

Must-do experiences

  • Visit the Mark Twain Boyhood Home for a literary journey.
  • Savor a slice of the famous Huck Finn pie at the Pie Pantry.
  • Explore the scenic views at Lover's Leap Park at sunset.
  • Don't miss the Hannibal History Museum for local tales.
  • Take a riverboat cruise on the Mississippi for stunning sights.
View all

Select your room type

Main Street Bed & Breakfast offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Deluxe Queen Suite
2 persons
400 sq. feet 
1 King-size bed
Shower
Coffee machine
Deluxe King Suite
2 persons
445 sq. feet 
1 King-size bed
Shower
Coffee machine

Price and Room Availability Calendar

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Facilities

Main Street Bed & Breakfast offers amenities for your comfortable stay and unforgettable experiences
Facilities: Perfect
9.3/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Free parking
  • VIP check-in/ -out
  • Express check-in/ -out
  • Concierge desk
  • No pets allowed
  • Security
  • Adults only
  • Smoke detectors
  • Fire extinguishers
  • Key access

Sports & Fitness

  • Canoeing
  • Hiking
  • Cycling
  • Bowling
  • Golf course
  • Fishing

Services

  • Valet parking
  • Housekeeping
  • Tours/Ticket assistance

Dining

  • In-room breakfast
  • Special diet menus

Spa & Leisure

  • Aqua park
  • Live entertainment
  • Night club
  • BBQ facilities
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Garden furniture
  • Tea and coffee facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
Show more

Main Street Bed & Breakfast Location

201 North Main Street, Hannibal, Missouri, United States, 63401
Map view
201 North Main Street, Hannibal, Missouri, United States, 63401
Nearby
Museum
Mark Twain Boyhood Home and Museum
1400 ft
Bridge
Mark Twain Memorial Lighthouse
1400 ft
Hannibal
Tom and Huck's Statue
1400 ft
Museum
Jim's Journey
1400 ft
211 Hill St
Haunted House on Hill Street Wax Museum
800 ft
Hannibal
Becky Thatcher's House
1400 ft
114 S 3rd St
Karlocks Kars and Pop Culture Museum
1100 ft
320 N 3rd St
Big River Train Town
1400 ft
600 Butler St
Molly Brown Museum and Home
1400 ft
Library
Hannibal Free Public Library
1800 ft
Park
Glascock's Landing
1400 ft
162-198 North St
Tom Sawyer and Huck Finn Statue
1100 ft
320 Broadway
Hannibal Parks & Recreation
1100 ft
Museum
Hannibal History Museum
1400 ft
600 Butler St
Molly Brown Birthplace
1400 ft
Store
Bluff City Theatre
1400 ft
Restaurants
The Brick Oven
100 ft
207 Center Street
Java Jive
200 ft
211 N Main St
Finn's Food and Spirits
200 ft
214 N Main St
Chocolaterie Stam
300 ft
103 N Main St
Riverside Restaurant
600 ft
111 Bird St
Mark Twain Dinette
1100 ft
400 N 3rd St
Explore Hannibal
Activities, Dining & Entertainment
Top Attractions
Activities
Dining
Entertainment
Mark Twain Boyhood Home and Museum
Mark Twain Boyhood Home and Museum
5 minutes' walk
Mark Twain's literary heritage showcased with exhibits and guided tours. A must-visit for literature enthusiasts.
Haunted House on Hill Street Wax Museum
Haunted House on Hill Street Wax Museum
3 minutes' walk
A captivating wax museum featuring eerie figures and local lore. Family-friendly and perfect for curious visitors.
Lovers Leap
19 minutes' walk
A scenic overlook with breathtaking views of the Mississippi River. Ideal for romantic moments or photography.
Rockcliffe Mansion
Rockcliffe Mansion
18 minutes' walk
A historic mansion offering guided tours that delve into its Victorian architecture and intriguing history.
Hiking at Sodalis Nature Preserve
25 minutes' walk
Trail systems through diverse habitats. Perfect for hiking, birdwatching, or enjoying nature's tranquility.
Mark Twain Cave Tours
6 minutes' drive
Explore the iconic cave with guided tours highlighting its geological features and Twain's history here.
Biking along the Riverfront Trail
5 minutes' drive
A scenic biking route alongside the river. Rentals available nearby to enjoy outdoor activity.
Yoga at Riverside Park
2 minutes' walk
Relaxing outdoor yoga sessions offered seasonally, ideal for unwinding amidst nature.
The Brick Oven
The Brick Oven
1 minute' walk
Quaint pizzeria with a cozy ambiance and a variety of specialty pizzas and local brews.
Finn's Food and Spirits
Finn's Food and Spirits
1 minute' walk
Casual dining with comfort food and a full bar. Known for its burgers and friendly atmosphere.
Riverside Restaurant
Riverside Restaurant
2 minutes' walk
Riverside views complement an extensive menu featuring local fare. Reservations recommended for peak hours.
Java Jive
Java Jive
1 minute' walk
Charming café known for its artisanal coffee and delectable pastries. Great for breakfast or a coffee break.
Riverland Theatre
5 minutes' drive
Local arts theater showcasing live performances and indie films. A great choice for evening entertainment.
The Gold Bar
2 minutes' walk
Lively bar with live music and trivia nights, creating a fun atmosphere for both locals and visitors.
Mark Twain Riverboat
10 minutes' walk
Experience the Mississippi River with scenic boat rides. Unique entertainment options include dinner cruises.
Hannibal History Museum
10 minutes' walk
Family-friendly museum featuring exhibits on Hannibal's history, including Twain memorabilia and events.
Getting around
City Centre
Hannibal5 min  ·  1400 ft
Airports
Quincy Regional (UIN)68 min  ·  27.8 mi
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Property information and rules
Check-in
from 14:00-20:00
Check-out
from 06:00-11:00
Guest Parking
Private parking is possible on site for free.
Internet
Wireless internet is available in for free.
Breakfast
At the hotel Main Street Bed & Breakfast guests are invited to a full breakfast served for free. 
Pets
Pets are not allowed.

Reviews and Ratings

Feedback about Main Street Bed & Breakfast from previous guests about their experience.
Review score
Based on 76 verified reviews
8.9/10
Great
94%
Recommend
Cleanliness
9.6/10
Comfort
9.5/10
Facilities
9.3/10
Free Wi-Fi
8.5/10
Location
9.6/10
Staff
9.5/10
Value for money
9.1/10
Guest reviews
based on 148 reviews
9.2/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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FAQs
About Main Street Bed & Breakfast
How far is Main Street Bed & Breakfast from Quincy Regional Airport?
Main Street Bed & Breakfast is 45 km from Quincy Regional Airport.
What time is check-in and check-out at Main Street Bed & Breakfast?
Check-in is at 14:00 and check-out is at 11:00.
What types of activities can guests enjoy at Main Street Bed & Breakfast?
Guests can enjoy activities such as cycling, fishing, hiking, and walking tours.
Is parking available at Main Street Bed & Breakfast?
Free private parking is available on-site, without the need for a reservation.
What dining options are available at Main Street Bed & Breakfast?
The hotel offers a continental breakfast daily, with breakfast in the room also available.
How close is Main Street Bed & Breakfast to nearby attractions like the Mark Twain Boyhood Home and Museum?
Main Street Bed & Breakfast is 0.5 km from the Mark Twain Boyhood Home and Museum.
What room amenities are offered at Main Street Bed & Breakfast?
Rooms include air conditioning, a flat-screen TV, a fridge, and a coffee machine.
Does Main Street Bed & Breakfast have any spa facilities?
Guests can enjoy a hot tub and spa bath in their rooms.
What languages do the staff at Main Street Bed & Breakfast speak?
Staff members are available to assist guests in English.
What recreational facilities are available for guests at Main Street Bed & Breakfast?
The hotel offers bike hire for guests to explore the area.
Which nearby restaurants can guests find while staying at Main Street Bed & Breakfast?
Nearby restaurants include Rumor Has IT, Java Jive, Finn's Food and Spirits, Due Amici Pizzeria, and Mark Twain Dinette, all within 0.5 km.

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Check-in
19Apr2026Select date
Check-out
20Apr2026Select date
Rooms and Guests2 Guests, 1 Room