Hampton Inn & Suites - Saint Louis South Interstate 55 Mehlville Exterior photoHampton Inn & Suites - Saint Louis South Interstate 55 Mehlville Exterior photoHampton Inn & Suites - Saint Louis South Interstate 55 Mehlville Facilities photo
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From199US$ /night
Check-in
19Apr2026Select date
Check-out
20Apr2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4200 Midamerica Lane, Mehlville, Missouri, United States, 63129
-
Near Sylvan Springs County Park
Perfect
9.1
9.4
/10
4.7
4.6
/5

Amenities

The Hampton Inn & Suites - Saint Louis South Interstate 55 offers an array of amenities for guests seeking convenience. Visitors can enjoy a 24-hour fitness center equipped with cardio and weight machines. The hotel also features an indoor pool, perfect for a refreshing swim any time of year.

Rooms

The hotel provides a variety of room options, including standard king and queen rooms, and larger suites designed for longer stays. Each room includes a refrigerator and microwave, catering to the needs of both business travelers and families. Guests can relax in comfortable accommodations fitted with premium bedding.

Dining

Complimentary breakfast options are served daily, featuring fresh waffles, omelets, and a selection of pastries. The hotel also provides grab-and-go breakfast options for guests on the move. Nearby dining choices include popular restaurants such as Cracker Barrel and Texas Roadhouse.

Location

Located just off Interstate 55, the hotel offers easy access to popular attractions such as the Gateway Arch and Busch Stadium. Guests can explore the historic neighborhoods of St. Louis, known for their unique architecture. Shopping and entertainment venues are within a short drive from the hotel.

Business Facilities

For business travelers, the Hampton Inn & Suites offers a fully equipped meeting room, accommodating up to 40 people. The business center is open 24/7, providing access to computers and printers for last-minute needs. Complimentary wireless internet support enhances work efficiency throughout the hotel.

Highlights

Location: Convenient access to St. Louis attractions

Amenities: Indoor pool & 24-hour fitness center

Dining: Complimentary breakfast served daily

Rooms: Standard king and queen rooms available

Must-do experiences

  • Visit the Missouri Botanical Garden for stunning landscapes year-round.
  • Savor toasted ravioli at Billy G's in South City for a local favorite.
  • Explore the eclectic shops at the Soulard Farmers Market on weekends.
  • Catch a game at Busch Stadium for the St. Louis Cardinals' home matches.
  • Discover art at the Contemporary Art Museum in Grand Center district.
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Select your room type

Hampton Inn & Suites - Saint Louis South Interstate 55 offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
King Room King Bed Non-Smoking
2 persons
305 sq. feet 
1 King-size bed
Shower
King Studio Suite Non-Smoking
3 persons
465 sq. feet 
1 King-size bed
Shower
King Room Accessible Tub Mobility Hearing Access or Non-Smoking
2 persons
305 sq. feet 
1 King-size bed
Shower
Queen Room Two Queen Beds Mobility Hearing Access or Non-Smoking
2 persons
305 sq. feet 
2 King Size Beds
Shower
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Facilities

Hampton Inn & Suites - Saint Louis South Interstate 55 offers amenities for your comfortable stay and unforgettable experiences
Facilities: Perfect
9.3/10Review score

General

  • No smoking on site
  • Free parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift
  • Vending machines

Sports & Fitness

  • Fitness centre

Services

  • Laundry
  • Dry cleaning

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots

Spa & Leisure

  • Indoor swimming pool

Room features

  • Free Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
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Hampton Inn & Suites - Saint Louis South Interstate 55 Location

4200 Midamerica Lane, Mehlville, Missouri, United States, 63129
Map view
4200 Midamerica Lane, Mehlville, Missouri, United States, 63129
Nearby
Assembly of God South Side Church
1000 ft
Saint Louis College of Health
1700 ft
Restaurants
Subway
2700 ft
4305 Butler Hill Rd Ste A
Hardee's
2600 ft
4321 Butler Hill Rd
Explore Mehlville
Explore Mehlville
Top Attractions
Activities
Dining
Entertainment
Missouri Civil War Museum
Missouri Civil War Museum
15 minutes' drive
Museum dedicated to Civil War history with exhibits and artifacts. Guided tours available for an insightful experience.
Saint Louis College of Health
8 minutes' walk
A local educational establishment with an impressive architecture, reflecting the community's commitment to healthcare education.
Suson Park
10 minutes' drive
A spacious park featuring picnic areas, walking trails, and a scenic pond, perfect for families and outdoor enthusiasts.
Mattiese Shopping Center
5 minutes' drive
Local shopping center with various retail options and eateries. Great spot for a casual afternoon out.
Tee Time Family Fun Center
5 minutes' drive
Family-friendly entertainment center offering mini-golf, arcade games, and laser tag. Ideal for thrill-seekers.
Yoga in the Park
10 minutes' drive
Outdoor yoga sessions held at Suson Park during summer. Relaxing atmosphere with beautiful scenery.
Subway
Subway
10 minutes' walk
Casual dining fast-food chain specializing in subs and salads. Great for a quick meal on the go.
Hardee's
Hardee's
10 minutes' walk
Casual fast-food restaurant known for its burgers and breakfast options. Family-friendly with a laid-back vibe.
Keller Plaza 8
10 minutes' drive
Local movie theater showcasing the latest films. Ideal for a family night out or a casual date.
BounceU of St. Louis
BounceU of St. Louis
10 minutes' drive
Indoor inflatable playground, great for kids and families. Offers various bounce events and birthday party options.
Getting around
City Centre
Mehlville2 min  ·  400 ft
Airports
Lambert (STL)63 min  ·  26.1 mi
MidAmerica St. Louis/Scott Air Force Base (BLV)95 min  ·  39.3 mi
Train
Shrewsbury Metrolink Station19 min  ·  7.8 mi
Sunnen Metrolink Station21 min  ·  8.6 mi
Bus
Bus stop4 min  ·  1000 ft
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
Wireless internet is available in the hotel rooms for free.
Breakfast
A buffet breakfast is served at affordable prices. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are allowed on request.
Year renovated:
2010
Number of floors:
4
Number of rooms:
91

Reviews and Ratings

Feedback about Hampton Inn & Suites - Saint Louis South Interstate 55 from previous guests about their experience.
Review score
Based on 192 verified reviews
9.2/10
Perfect
93%
Recommend
Breakfast
8.3/10
Cleanliness
9.3/10
Comfort
9.2/10
Facilities
9.3/10
Free Wi-Fi
9.1/10
Location
9.2/10
Paid Wi-Fi
7.5/10
Staff
9.2/10
Value for money
8.6/10
Guest reviews
based on 261 reviews
9.1/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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FAQs
About Hampton Inn & Suites - Saint Louis South Interstate 55
What time is check-in and check-out at Hampton Inn & Suites - Saint Louis South Interstate 55?
Check-in is at 15:00 and check-out is at 11:00.
Is parking available at Hampton Inn & Suites - Saint Louis South Interstate 55?
The hotel offers free public parking on-site.
What are the nearby attractions to Hampton Inn & Suites - Saint Louis South Interstate 55?
Nearby attractions include Cahokia Mounds State Park (40 km) and the St. Louis Zoo (30 km).
What amenities can guests expect in the rooms at Hampton Inn & Suites - Saint Louis South Interstate 55?
Rooms are equipped with flat-screen TVs, microwaves, refrigerators, and work desks.
What dining options are available at Hampton Inn & Suites - Saint Louis South Interstate 55?
A complimentary breakfast buffet with hot and cold options is served every morning.
Does Hampton Inn & Suites - Saint Louis South Interstate 55 have a swimming pool or fitness center?
Guests can enjoy the indoor pool and fitness center, which are open year-round.
What business services does Hampton Inn & Suites - Saint Louis South Interstate 55 provide?
The hotel features a business center equipped with computers, printer, and meeting facilities.
How far is Hampton Inn & Suites - Saint Louis South Interstate 55 from Lambert Airport?
The hotel is approximately 45 km from Lambert Airport.
Are there any facilities at Hampton Inn & Suites - Saint Louis South Interstate 55 for guests with disabilities?
The hotel has accessible facilities designed for disabled guests.

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19Apr2026Select date
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Rooms and Guests2 Guests, 1 Room