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From199US$ /night
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09Jan2026Select date
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Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4200 Midamerica Lane, Mehlville, Missouri, United States, 63129
-
Near Sylvan Springs County Park
Perfect
9.0
9.5
/10
4.8
4.6
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Location

Hampton Inn & Suites - Saint Louis South Interstate 55 is strategically located just off Interstate 55, providing easy access to downtown Saint Louis. The hotel is a short drive from the Gateway Arch and the Anheuser-Busch Brewery. Nearby attractions include the St. Louis Zoo and the Missouri Botanical Garden.

Accommodations

The hotel offers 85 inviting rooms and suites designed for convenience with a variety of options, including King Studios. Each room includes a work desk and ergonomic chair, ensuring a comfortable workspace. Guests can also enjoy the convenience of a mini-refrigerator and microwave in select accommodations.

Dining

Hampton Inn & Suites offers a fresh and free hot breakfast each morning featuring a variety of options including waffles, oatmeal, and fruit. The hotel also provides a snack shop, ensuring quick access to snacks and drinks throughout the day. Room service is available for guests who prefer to dine in their accommodations.

Fitness and Business

The hotel includes a well-equipped fitness center, allowing guests to maintain their workout regimen during their stay. A business center is available with printing and copying services to assist corporate travelers. Meeting space can accommodate gatherings for up to 60 guests.

Family Amenities

Hampton Inn & Suites provides family-friendly amenities to enhance the stay for guests traveling with children. Cribs and rollaway beds are available at no extra charge, accommodating families comfortably. The hotel's location means easy access to local attractions entertainment for all ages.

Highlights

Location: Near downtown Saint Louis attractions

Rooms: 85 inviting rooms and suites

Dining: fresh and free hot breakfast

Fitness: well-equipped fitness center

Must-do experiences

  • Visit the Missouri Botanical Garden for stunning landscapes year-round.
  • Savor toasted ravioli at Billy G's in South City for a local favorite.
  • Explore the eclectic shops at the Soulard Farmers Market on weekends.
  • Catch a game at Busch Stadium for the St. Louis Cardinals' home matches.
  • Discover art at the Contemporary Art Museum in Grand Center district.
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Select your room type

The hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
King Room King Bed Non-Smoking
2 persons
28 m² 
1 King-size bed
Shower
Room Two Queen Beds Non-Smoking
4 persons
34 m² 
2 King Size Beds
Shower
King Studio Suite Non-Smoking
3 persons
43 m² 
1 King-size bed
Shower
King Room Accessible Tub Mobility Hearing Access or Non-Smoking
2 persons
28 m² 
1 King-size bed
Shower
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Facilities

The hotel offers amenities for your comfortable stay and unforgettable experiences

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift
  • Vending machines

Sports & Fitness

  • Fitness centre

Services

  • Laundry
  • Dry cleaning

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots

Spa & Leisure

  • Indoor swimming pool

Room features

  • Free Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
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Location

4200 Midamerica Lane, Mehlville, Missouri, United States, 63129
Map view
4200 Midamerica Lane, Mehlville, Missouri, United States, 63129
Nearby
Assembly of God South Side Church
280 m
Saint Louis College of Health
500 m
Restaurants
Subway
800 m
4305 Butler Hill Rd Ste A
Hardee's
770 m
4321 Butler Hill Rd
Explore Mehlville
Explore Mehlville
Top Attractions
Activities
Dining
Entertainment
Missouri Civil War Museum
Missouri Civil War Museum
15 minutes' drive
Museum dedicated to Civil War history with exhibits and artifacts. Guided tours available for an insightful experience.
Saint Louis College of Health
8 minutes' walk
A local educational establishment with an impressive architecture, reflecting the community's commitment to healthcare education.
Suson Park
10 minutes' drive
A spacious park featuring picnic areas, walking trails, and a scenic pond, perfect for families and outdoor enthusiasts.
Mattiese Shopping Center
5 minutes' drive
Local shopping center with various retail options and eateries. Great spot for a casual afternoon out.
Tee Time Family Fun Center
5 minutes' drive
Family-friendly entertainment center offering mini-golf, arcade games, and laser tag. Ideal for thrill-seekers.
Yoga in the Park
10 minutes' drive
Outdoor yoga sessions held at Suson Park during summer. Relaxing atmosphere with beautiful scenery.
Subway
Subway
10 minutes' walk
Casual dining fast-food chain specializing in subs and salads. Great for a quick meal on the go.
Hardee's
Hardee's
10 minutes' walk
Casual fast-food restaurant known for its burgers and breakfast options. Family-friendly with a laid-back vibe.
Keller Plaza 8
10 minutes' drive
Local movie theater showcasing the latest films. Ideal for a family night out or a casual date.
BounceU of St. Louis
BounceU of St. Louis
10 minutes' drive
Indoor inflatable playground, great for kids and families. Offers various bounce events and birthday party options.
Getting around
City Centre
Mehlville31 min  ·  20.5 km
Airports
St. Louis Lambert International Airport (STL)63 min  ·  42.0 km
Belleville, IL (BLV)95 min  ·  63.3 km
Train
Gateway Transportation Center31 min  ·  20.3 km
Bus
Bus stop4 min  ·  300 m
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
is available in for free.
Breakfast
A buffet breakfast is served at affordable prices. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are allowed on request.
Year renovated:
2010
Number of floors:
4
Number of rooms:
91
FAQs
About Hampton Inn & Suites - Saint Louis South Interstate 55
What time is check-in and check-out at Hampton Inn & Suites - Saint Louis South Interstate 55?
Check-in is at 15:00 and check-out is at 11:00.
Is parking available at Hampton Inn & Suites - Saint Louis South Interstate 55?
The hotel offers free public parking on-site.
What are the nearby attractions to Hampton Inn & Suites - Saint Louis South Interstate 55?
Nearby attractions include Cahokia Mounds State Park (40 km) and the St. Louis Zoo (30 km).
What amenities can guests expect in the rooms at Hampton Inn & Suites - Saint Louis South Interstate 55?
Rooms are equipped with flat-screen TVs, microwaves, refrigerators, and work desks.
What dining options are available at Hampton Inn & Suites - Saint Louis South Interstate 55?
A complimentary breakfast buffet with hot and cold options is served every morning.
Does Hampton Inn & Suites - Saint Louis South Interstate 55 have a swimming pool or fitness center?
Guests can enjoy the indoor pool and fitness center, which are open year-round.
What business services does Hampton Inn & Suites - Saint Louis South Interstate 55 provide?
The hotel features a business center equipped with computers, printer, and meeting facilities.
How far is Hampton Inn & Suites - Saint Louis South Interstate 55 from Lambert Airport?
The hotel is approximately 45 km from Lambert Airport.
Are there any facilities at Hampton Inn & Suites - Saint Louis South Interstate 55 for guests with disabilities?
The hotel has accessible facilities designed for disabled guests.

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Check-in
09Jan2026Select date
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Rooms and Guests2 Guests, 1 Room

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Hampton Inn & Suites - Saint Louis South Interstate 55 Mehlville Exterior photo

Hampton Inn & Suites - Saint Louis South Interstate 55

9.0
Perfect259 reviews
20.5 km from center
179 US$
199 US$
per night
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