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From82US$ /night
Check-in
18Apr2026Select date
Check-out
19Apr2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

Via Cola Di Rienzo 23, Rome, Italy, 00192
-
Close to Piazza del Popolo
Great
8.3
8.1
/10
3.3
3.7
/5

Rooms

Hotel Twenty One offers 93 accommodations with custom-made designer furniture and LCD satellite TVs. The Deluxe double rooms provide impressive views of the city's landmarks, each featuring a private terrace. Junior suites come equipped with Jacuzzis and spacious living areas, enhancing the stay with comfort and convenience.

Dining

Bistro 21 serves a variety of traditional Italian dishes prepared with high-quality ingredients. Guests can enjoy a rich buffet for lunch and an extensive menu for dinner, showcasing Mediterranean flavors. The happy hour features cocktails and appetizers, providing a relaxed dining atmosphere.

Location

Situated in the Prati district, Hotel Twenty One is strategically positioned between the Vatican Museums and the Spanish Steps. The Lepanto underground station is just 400 meters away, providing direct access to major attractions. Guests can easily stroll to points of interest, including Piazza Navona and the Trevi Fountain.

Family Amenities

Hotel Twenty One offers family-friendly accommodations, with connecting rooms available for larger groups. Each connected room setup features two bathrooms, ensuring comfort for families traveling together. The location near key attractions makes it convenient for family outings.

Business Connectivity

A 24-hour reception is available to assist business travelers with their arrangements. The hotel's location allows quick access to various corporate districts and conference venues throughout Rome. Free internet access enables seamless communication and productivity during stays.

Highlights

Location: halfway between St Peter's and the Spanish Steps

Dining: traditional Italian dishes at Bistro 21

Rooms: Junior suites with Jacuzzis

Family: Two rooms connected by a door

Must-do experiences

  • Taste authentic carbonara at Trattoria Da Enzo in Trastevere.
  • Visit the Galleria Borghese for stunning art and serene gardens.
  • Explore the quiet streets of Testaccio for local markets and food.
  • Discover the ancient ruins at Ostia Antica, a hidden gem nearby.
  • Enjoy gelato at Giolitti near the Pantheon, a local favorite.
View all

Select your room type

Twentyone Hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Twin Room
2 persons
195 sq. feet 
2 Single beds
Shower
Heating
Triple Room
2 persons
240 sq. feet 
3 Single beds
Shower
Heating
Double Room
2 persons
195 sq. feet 
1 King-size bed
Shower
Heating
Deluxe Twin Room
2 persons
250 sq. feet 
2 Single beds
Shower
Heating
Click button to see more rooms
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Facilities

Twentyone Hotel offers amenities for your comfortable stay and unforgettable experiences
Facilities: Great
8.2/10Review score

General

  • Non-smoking rooms
  • Wi-Fi
  • On-site car park
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • No pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • Barber shop
  • Coffee shop
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre

Services

  • Paid airport shuttle
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Packed lunches
  • Special diet menus

Business

  • Fax/Photocopying

Children

  • Cots
  • Children's buffet

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Garden area
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries
  • Sink

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Carpeted floor
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Dining Onsite

At the Twentyone Hotel, dining becomes a delightful exploration of flavors and cultures. Guests can indulge in an array of traditional Roman and classic Italian dishes at Vista, while enjoying a modern ambiance infused with charm. Each meal invites both hearty and refined experiences, making every visit memorable.
Twentyone Hotel Rome Restaurant photo
Twentyone Hotel Rome Restaurant photo
Twentyone Hotel Rome Restaurant photo

Vista

International with a focus on traditional Roman and classic Italian dishes
Ambiance
Modern setting with an inviting atmosphere, perfect for both casual dining and special occasions.
Key Offerings
A rich and varied buffet featuring unique culinary creations, complemented by a large selection of wines and champagne for added indulgence.
Reservation
Reservations recommended.
Open daily from 11:30 to 23:30.

Twentyone Hotel Location

Via Cola Di Rienzo 23, Rome, Italy, 00192
Map view
Via Cola Di Rienzo 23, Rome, Italy, 00192
Nearby
Bridge
Castel Sant'Angelo
3500 ft
Square
Piazza del Popolo
2500 ft
Bridge
St. Angelo Bridge
3600 ft
Church
Church of Santa Maria del Popolo
2300 ft
Church
Basilica of Sant' Agostino
3400 ft
Restaurants
Bistro' 21
100 ft
Via Cola di Rienzo 23 Hotel Twenty One
Cantieri Bistrot
300 ft
Via Cola di Rienzo 16
Le Sicilianedde
300 ft
Via Cola di Rienzo
La Pinseria Prati
300 ft
Via Lucrezio Caro 60
Pasticceria Sanzini
500 ft
Via Valadier
VINO e FOCACCIA
500 ft
Piazza Cola di Rienzo 83/A
Grotta Azzurra
700 ft
Via Cicerone 62a
Quelli del bar Cicerone
600 ft
Via Cicerone 68
Ristorante Visconti 2.0
800 ft
Via Ennio Quirino Visconti 83
Explore Rome
Explore Rome's Charm
Top Attractions
Activities
Dining
Entertainment
Piazza Navona
Piazza Navona
16 minutes' walk
A stunning square famous for its Baroque architecture and lively atmosphere, featuring impressive fountains and street artists.
Vatican Museums
Vatican Museums
20 minutes' walk
Home to extraordinary art collections, including the Sistine Chapel, guided tours enhance your visit to this cultural treasure.
Castel Sant'Angelo
Castel Sant'Angelo
13 minutes' walk
A historic fortress offering panoramic views, the castle's rich history and museum make it a must-visit attraction.
St. Peter's Basilica
St. Peter's Basilica
20 minutes' walk
One of the largest churches in the world, its magnificent dome and stunning interiors are breathtaking highlights of Vatican City.
Biking along the Tiber
9 minutes walking
Enjoy a scenic bike ride along the Tiber River, with rental services nearby that cater to all skill levels and ages.
Relaxing at Fiume Tevere Park
9 minutes' walk
A peaceful park ideal for leisurely strolls or picnics by the river, perfect for unwinding amidst the city's hustle.
Bistro' 21
Bistro' 21
1 minute' walk
A charming eatery with Italian favorites, known for its fresh ingredients and inviting ambiance. Reservations recommended.
La Pinseria Prati
La Pinseria Prati
1 minute' walk
Specializes in authentic Roman-style pizzas, this casual spot offers a delicious menu and a warm atmosphere.
Jazz Club
15 minutes' walk
A vibrant venue featuring live jazz performances, the club has a cozy atmosphere perfect for music lovers of all ages.
Teatro Argentina
20 minutes' walk
Catch a captivating theater production at this historic venue, with a diverse lineup that accommodates all interests.
Getting around
City Centre
Rome28 min  ·  1.4 mi
Airports
Ciampino (CIA)28 min  ·  11.6 mi
Fiumicino (FCO)45 min  ·  18.4 mi
Train
Flaminio Train Station10 min  ·  2700 ft
Underground
Lepanto Metro Station5 min  ·  1400 ft
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Property information and rules
Check-in
from 15:00-23:59
Check-out
from 07:00-11:00
Guest Parking
Private parking is possible on site (reservation might be needed) at EUR 35 per day.
Internet
Wireless internet is available in for free.
Breakfast
The hotel Twentyone provides visitors with a free full breakfast. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are not allowed.
Languages
English, German, Spanish, Italian, Russian, Moldovan
Year renovated:
2009
Number of floors:
6
Number of rooms:
88

Reviews and Ratings

Feedback about Twentyone Hotel from previous guests about their experience.
Review score
Based on 1391 verified reviews
8.1/10
Great
85%
Recommend
Breakfast
8.5/10
Cleanliness
8.6/10
Comfort
8.5/10
Facilities
8.2/10
Free Wi-Fi
8.2/10
Location
9.2/10
Paid Wi-Fi
7.1/10
Staff
8.7/10
Value for money
7.9/10
Guest reviews
based on 1391 reviews
8.1/10
based on 1904 reviews
4/5
based on 3688 reviews
8.3/10
Penelope from Greece
Single
Double Room
4 nights in October 2025
|
Reviewed:November 14, 2025
7/10
fresh pastriesfruit optionstvinadequate air conditioningfirm bedroom description
Breakfast included many options, such as fresh pastries and fruit. The rooms are equipped with a tv. I found the location not far from the downtown area..
The room did not completely match what I had booked. I hoped for a quiet room. The air conditioning was poor, and the bed was hard. I did not receive information in a timely manner.
0 Helpful
FAQs
About Twentyone Hotel
What are the check-in and check-out times at Twentyone Hotel?
Check-in is from 15:00 and check-out is by 11:00.
How far is Twentyone Hotel from St. Peter's Basilica?
St. Peter's Basilica is a 15-minute walk from the hotel.
Is there an airport shuttle available at Twentyone Hotel?
The hotel offers a paid airport shuttle service.
What amenities are included in the rooms at Twentyone Hotel?
Rooms feature air conditioning, an LCD satellite TV, a minibar, free Wi-Fi, and coffee/tea making facilities.
What dining options are available at Twentyone Hotel?
The hotel has an on-site restaurant serving traditional Roman and classic Italian dishes.
Is there parking available at Twentyone Hotel?
Private parking is available on-site for 35 EUR per day, and a reservation is needed.
What is the distance from Twentyone Hotel to the nearest metro station?
Lepanto Metro Station is 500 meters from the hotel.
Does Twentyone Hotel offer breakfast?
A breakfast buffet is available at an additional charge of 15 EUR.
What fitness facilities are available at Twentyone Hotel?
Guests have access to a fitness center on-site.
What sightseeing attractions are close to Twentyone Hotel?
Nearby attractions include the Vatican Museums and Piazza Navona, both within 1 km.
Does Twentyone Hotel feature any special views?
The hotel offers picturesque views of St. Peter's Dome from its rooftop restaurant.

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Check-in
18Apr2026Select date
Check-out
19Apr2026Select date
Rooms and Guests2 Guests, 1 Room