What are the check-in and check-out times at Twentyone Hotel?
Check-in is from 15:00 and check-out is by 11:00.
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Twentyone Hotel, Rome
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Key details
About the Hotel
Via Cola Di Rienzo 23, Rome, 00192,
- Close to Piazza del Popolo
Great
8.4
8.1
3.5
3.7
4-star hotel near Vatican with stunning city views
Rooms
Hotel Twenty One offers 93 accommodations with custom-made designer furniture and LCD satellite TVs. The
Dining
Location
Situated in the Prati district, Hotel Twenty One is strategically positioned between the Vatican Museums and the Spanish Steps. The Lepanto underground station is just 400 meters away, providing direct access to major attractions. Guests can easily stroll to points of interest, including Piazza Navona and the Trevi Fountain.
Family Amenities
Hotel Twenty One offers
Business Connectivity
A 24-hour reception is available to assist business travelers with their arrangements. The hotel's location allows quick access to various corporate districts and conference venues throughout Rome.
Highlights
Location: halfway between St Peter's and the Spanish Steps
Dining: traditional Italian dishes at Bistro 21
Rooms: Junior suites with Jacuzzis
Family: Two rooms connected by a door
Must-do experiences
- Taste authentic carbonara at Trattoria Da Enzo in Trastevere.
- Visit the Galleria Borghese for stunning art and serene gardens.
- Explore the quiet streets of Testaccio for local markets and food.
- Discover the ancient ruins at Ostia Antica, a hidden gem nearby.
- Enjoy gelato at Giolitti near the Pantheon, a local favorite.
Select your room type
Twentyone Hotel offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
- Twin Room2 persons18 sq. feet2 Single bedsAir conditioningHeatingroom details
- Triple Room2 persons22 sq. feet3 Single bedsAir conditioningHeatingroom details
- Double Room2 persons18 sq. feet1 King-size bedAir conditioningHeatingroom details
Show all rooms
Price and Room Availability Calendar
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Check-in/ Check-out
Facilities
Twentyone Hotel offers amenities for your comfortable stay and unforgettable experiences
General
- Non-smoking rooms
- Wi-Fi
- Parking
- Safe deposit box
- 24-hour reception
- Express check-in/ -out
- No pets allowed
- Rooms/ Facilities for disabled
- Wheelchair access
- Security
- Luggage storage
- Allergy-free rooms
- Lift
- Barber shop
- Coffee shop
- Smoke detectors
- Electric vehicle charging station
- Fire extinguishers
- Key card access
Sports & Fitness
- Fitness centre
Services
- Paid airport shuttle
- Room service
- Housekeeping
- Laundry
- Dry cleaning
- Tours/Ticket assistance
- Welcome drink
Dining
- In-room breakfast
- Restaurant
- Snack bar
- Bar/ Lounge area
- Packed lunches
- Special diet menus
Business
- Fax/Photocopying
Children
- Cots
- Children's buffet
Facilities for people with disabilities
- Toilet for disabled
- Bathroom for disabled
Spa & Leisure
- Garden area
- Leisure/ TV room
Room features
- Air conditioning
- Heating
- Mini-bar
- Soundproofed rooms
- Sitting area
- Terrace
- Garden furniture
- Tea and coffee facilities
- Ironing facilities
Bathroom
- Free toiletries
- Sink
Media
- Flat-screen TV
- AM/FM alarm clock
Room decor
- Carpeted floor
Show more
Dining Onsite
At the Twentyone Hotel, dining becomes a delightful exploration of flavors and cultures. Guests can indulge in an array of traditional Roman and classic Italian dishes at Vista, while enjoying a modern ambiance infused with charm. Each meal invites both hearty and refined experiences, making every visit memorable.
Twentyone Hotel Location
Via Cola Di Rienzo 23, Rome, 00192,
Explore Rome
Explore Rome's Charm
Piazza Navona
16 minutes' walk
A stunning square famous for its Baroque architecture and lively atmosphere, featuring impressive fountains and street artists.
Vatican Museums
20 minutes' walk
Home to extraordinary art collections, including the Sistine Chapel, guided tours enhance your visit to this cultural treasure.
Castel Sant'Angelo
13 minutes' walk
A historic fortress offering panoramic views, the castle's rich history and museum make it a must-visit attraction.
St. Peter's Basilica
20 minutes' walk
One of the largest churches in the world, its magnificent dome and stunning interiors are breathtaking highlights of Vatican City.
Biking along the Tiber
9 minutes walking
Enjoy a scenic bike ride along the Tiber River, with rental services nearby that cater to all skill levels and ages.
Relaxing at Fiume Tevere Park
9 minutes' walk
A peaceful park ideal for leisurely strolls or picnics by the river, perfect for unwinding amidst the city's hustle.
Bistro' 21
1 minute' walk
A charming eatery with Italian favorites, known for its fresh ingredients and inviting ambiance. Reservations recommended.
La Pinseria Prati
1 minute' walk
Specializes in authentic Roman-style pizzas, this casual spot offers a delicious menu and a warm atmosphere.
Jazz Club
15 minutes' walk
A vibrant venue featuring live jazz performances, the club has a cozy atmosphere perfect for music lovers of all ages.
Teatro Argentina
20 minutes' walk
Catch a captivating theater production at this historic venue, with a diverse lineup that accommodates all interests.
Getting around
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Property information and rules
Check-in
from 15:00-23:59
Check-out
from 07:00-11:00
Guest Parking
Private parking is possible on site (reservation might be needed) at true.
Internet
Wireless internet is available in the entire hotel for free.
Breakfast
A full breakfast is served at the price of EUR 15.0 per person.
Children & extra beds
There are no cots provided in a room.
Pets
Pets are not allowed.
Languages
English, German, Spanish, Italian, Russian, Moldovan
Year renovated:
2009
Number of floors:
6
Number of rooms:
84
Reviews and Ratings
Feedback about Twentyone Hotel from previous guests about their experience.
Guest reviewsbased on 1447 reviews
kelly from ireland
Family with children
family room
4 nights in November 2025
|
Reviewed: January 14, 2026
9/10
breakfast buffet rooftop setting powerful shower
The breakfast buffet was amazing!!! it had great variety and the rooftop setting added a beautiful view. the location was very convenient for exploring. I found it easy to reach many attractions. the bathroom featured a powerful warm shower, it was so relaxing!!!
the lift was quite small, it felt a little cramped at times.
0 Helpful
Nicole from Australia
Couple
Deluxe Double Room
3 nights in November 2025
|
Reviewed: January 13, 2026
7/10
nice breakfast zone friendly staff quiet street small room curtain problem anniversary trip
The hotel provided a breakfast zone. It had a view and friendly staff. The location is nice, with quiet streets at night. The room was clean every day and fresh towels was provided.
The room looked at the atrium. I could not open the curtains at night. The room was very small and I asked for a nice room due to anniversary trip. The hotel did ignore it.
0 Helpful
Ernest from United Kingdom
Family with children
Triple Room
5 nights in October 2025
|
Reviewed: January 11, 2026
9/10
enjoyable stay
scrambled eggs major attractions
i enjoyed the very good breakfastwith scrambled eggs. the hotel location is perfect i found. all major attractions were within walking distance.
0 Helpful
Zoe from United Kingdom
Double Room
4 nights in November 2025
|
Reviewed: January 04, 2026
8/10
local eateries double room helpful staff
my double room was clean. the location allowed easy access to many shops and restaurants. the staff provided helpful recommendations for local eateries.
the breakfast assortment was limited to me.
0 Helpful
Leigh from United Kingdom
Couple
Double Room
4 nights in November 2025
|
Reviewed: December 04, 2025
6/10
dated decor hard bed
the room was dark the decor felt a bit dated with some questionable stains on the walls the bed was firmer than i prefer a real test of endurance for my back also the lack of a proper door lock on the bathroom added a certain level of vulnerability i wasn't quite ready for it seems discretion isn't always the better part of valour here
0 Helpful
Penelope from Greece
Single
Double Room
4 nights in October 2025
|
Reviewed: November 14, 2025
7/10
fresh pastries fruit options tv inadequate air conditioning firm bed room description
Breakfast included many options, such as fresh pastries and fruit. The rooms are equipped with a tv. I found the location not far from the downtown area..
The room did not completely match what I had booked. I hoped for a quiet room. The air conditioning was poor, and the bed was hard. I did not receive information in a timely manner.
0 Helpful
Show more reviews
FAQs
About Twentyone Hotel
How far is Twentyone Hotel from St. Peter's Basilica?
St. Peter's Basilica is a 15-minute walk from the hotel.
Is there an airport shuttle available at Twentyone Hotel?
The hotel offers a paid airport shuttle service.
What amenities are included in the rooms at Twentyone Hotel?
Rooms feature air conditioning, an LCD satellite TV, a minibar, free Wi-Fi, and coffee/tea making facilities.
What dining options are available at Twentyone Hotel?
The hotel has an on-site restaurant serving traditional Roman and classic Italian dishes.
Is there parking available at Twentyone Hotel?
Private parking is available on-site for 35 EUR per day, and a reservation is needed.
What is the distance from Twentyone Hotel to the nearest metro station?
Lepanto Metro Station is 500 meters from the hotel.
Does Twentyone Hotel offer breakfast?
A breakfast buffet is available at an additional charge of 15 EUR.
What fitness facilities are available at Twentyone Hotel?
Guests have access to a fitness center on-site.
What sightseeing attractions are close to Twentyone Hotel?
Nearby attractions include the Vatican Museums and Piazza Navona, both within 1 km.
Does Twentyone Hotel feature any special views?
The hotel offers picturesque views of St. Peter's Dome from its rooftop restaurant.
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